To those still intent on keeping up with this subject :
On May 2014, the respected and international medical reference “National Cancer Institute” published an article called “Cannabis and Cannabinoids “, supported with 39 Studies (one of which, btw, is co-authored by Prof. Cristina Sanchez, whom I contacted towards a recommendation to obtain commercial CBD).
Under its “Laboratory/Animal/Preclinical Studies” tab, one can read :
- One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors
- Cannabinoids may cause antitumor effects by various mechanisms, including induction of cell death, inhibition of cell growth, and inhibition of tumor angiogenesis invasion and metastasis
- Cannabinoids appear to kill tumor cells but do not affect their nontransformed counterparts and may even protect them from cell death.
- An in vitro study of the effect of CBD on programmed cell death in breast cancer cell lines found that CBD induced programmed cell death, independent of the CB1, CB2, or vanilloid receptors. CBD inhibited the survival of both estrogen receptor–positive and estrogen receptor–negative breast cancer cell lines, inducing apoptosis in a concentration-dependent manner while having little effect on nontumorigenic, mammary cells.
- CBD has also been demonstrated to exert a chemopreventive effect in a mouse model of colon cancer
- In in vitro experiments involving colorectal cancer cell lines, the investigators found that CBD protected DNA from oxidative damage, increased endocannabinoid levels, and reduced cell proliferation.
- CBD may also enhance uptake of cytotoxic drugs into malignant cells. This suggests that coadministration of CBD with cytotoxic agents may increase drug uptake and potentiate cell death in human glioma cells.
- Cannabinoids may also contribute to pain modulation through an anti-inflammatory mechanism
Not only Amazing …. but Fascinating !
And keep in mind the date of these “appear to ”, “may cause” and “may have”: May 2014. Meaning, “and so it begins …” ? For we’re still in the “Animal/Preclinical Studies” domain.
Perhaps not due to chance, a US company, called “Inergetics” (a “a leading developer of nutritional supplements”), this August 2014, announced the “beginning of the second phase of development towards the launch of its proprietary line of natural cannabidiol (CBD)-based nutritional supplements”.
Also perhaps not due to chance, a Canadian company, called “Global Hemp Group”, this July 2014, announced “that the first tranche of the non-brokered private placement announced May 15, 2014 is now closed”, meaning (to me, that is !) … time has come to get greedy . Their “Business Philosophy”? to market “products that will be recognized as leading global brands, it will operate in the automotive, building materials, biocomposites, energy-related markets, food” (and, yes, you got it) “ nutritional supplements & nutriceuticals, and pharmaceuticals markets”.
Also, how about an organization called “Project CBD” ? Their site can be found here http://www.projectcbd.org/ and I have not been able to ascertain their inception, but their “copyright” is from 2014. It is a very useful tool for to understand CBD … and also for US people to know where and to whom they can buy the substance. Worth (definitely) a check.
All this to say,
No, there’s not only smoke in this.
And time will tell ….
Full NCI article here : http://www.cancer.gov/cancertopics/pdq/ ... onal/page4
Inergetics announcement here : http://www.prnewswire.com/news-releases ... 84171.html
Global Hemp announcement here : http://globalhempgroup.com/global-hemp- ... financing/